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allen mouse brain atlas  (Human Protein Atlas)

 
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    Human Protein Atlas allen mouse brain atlas
    A Circular heatmap of the distribution of the eight neurological phenotypes across the 151 NDD datasets. B The signed -log 10 P value of the Cerebellar Purkinje cell layer formation GO-BP term across the different datasets. A negative and positive signed -log 10 P value were calculated through Gene Set Enrichment Analysis (GSEA) and indicates down- and upregulated expression, respectively. C log 2 odds ratio (OR) of differential expression in seizure- versus non-seizure-associated neurodevelopmental disorders for all genes associated with cerebellar Purkinje cell layer formation. LHX1 has the highest OR. The lines indicate different types of protein-protein and gene-gene relationships from GeneMANIA (version 3.5.3). D log 2 FC profile and their 95% confidence interval of the LHX1 gene in seizure- and non-seizure-associated neurodevelopmental disorders. E LHX1 expression levels across different <t>brain</t> regions in six different datasets available from the Human Protein <t>Atlas:</t> HPA (Human), FANTOM, GTEx, HPA (Pig), HPA <t>(Mouse),</t> and <t>Allen</t> Mouse Brain Atlas. The Z-score was calculated for each dataset separately. F UMAP plot of the cerebellar vermis scRNA-seq data from the Human Brain Atlas v1.0. The LHX1 expression in the different superclusters is shown. Specifically, 51 and 28% of the cerebellar inhibitory and upper rhombic lip cells, respectively, express LHX1 .
    Allen Mouse Brain Atlas, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/allen+mouse+brain+atlas/pmc12159135-225-33-19?v=Human+Protein+Atlas
    Average 90 stars, based on 1 article reviews
    allen mouse brain atlas - by Bioz Stars, 2026-07
    90/100 stars

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    1) Product Images from "Integrative analysis of 115 transcriptomic studies decodes the molecular landscape of neurodevelopmental disorders"

    Article Title: Integrative analysis of 115 transcriptomic studies decodes the molecular landscape of neurodevelopmental disorders

    Journal: Communications Biology

    doi: 10.1038/s42003-025-08330-2

    A Circular heatmap of the distribution of the eight neurological phenotypes across the 151 NDD datasets. B The signed -log 10 P value of the Cerebellar Purkinje cell layer formation GO-BP term across the different datasets. A negative and positive signed -log 10 P value were calculated through Gene Set Enrichment Analysis (GSEA) and indicates down- and upregulated expression, respectively. C log 2 odds ratio (OR) of differential expression in seizure- versus non-seizure-associated neurodevelopmental disorders for all genes associated with cerebellar Purkinje cell layer formation. LHX1 has the highest OR. The lines indicate different types of protein-protein and gene-gene relationships from GeneMANIA (version 3.5.3). D log 2 FC profile and their 95% confidence interval of the LHX1 gene in seizure- and non-seizure-associated neurodevelopmental disorders. E LHX1 expression levels across different brain regions in six different datasets available from the Human Protein Atlas: HPA (Human), FANTOM, GTEx, HPA (Pig), HPA (Mouse), and Allen Mouse Brain Atlas. The Z-score was calculated for each dataset separately. F UMAP plot of the cerebellar vermis scRNA-seq data from the Human Brain Atlas v1.0. The LHX1 expression in the different superclusters is shown. Specifically, 51 and 28% of the cerebellar inhibitory and upper rhombic lip cells, respectively, express LHX1 .
    Figure Legend Snippet: A Circular heatmap of the distribution of the eight neurological phenotypes across the 151 NDD datasets. B The signed -log 10 P value of the Cerebellar Purkinje cell layer formation GO-BP term across the different datasets. A negative and positive signed -log 10 P value were calculated through Gene Set Enrichment Analysis (GSEA) and indicates down- and upregulated expression, respectively. C log 2 odds ratio (OR) of differential expression in seizure- versus non-seizure-associated neurodevelopmental disorders for all genes associated with cerebellar Purkinje cell layer formation. LHX1 has the highest OR. The lines indicate different types of protein-protein and gene-gene relationships from GeneMANIA (version 3.5.3). D log 2 FC profile and their 95% confidence interval of the LHX1 gene in seizure- and non-seizure-associated neurodevelopmental disorders. E LHX1 expression levels across different brain regions in six different datasets available from the Human Protein Atlas: HPA (Human), FANTOM, GTEx, HPA (Pig), HPA (Mouse), and Allen Mouse Brain Atlas. The Z-score was calculated for each dataset separately. F UMAP plot of the cerebellar vermis scRNA-seq data from the Human Brain Atlas v1.0. The LHX1 expression in the different superclusters is shown. Specifically, 51 and 28% of the cerebellar inhibitory and upper rhombic lip cells, respectively, express LHX1 .

    Techniques Used: Expressing, Quantitative Proteomics



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    A Circular heatmap of the distribution of the eight neurological phenotypes across the 151 NDD datasets. B The signed -log 10 P value of the Cerebellar Purkinje cell layer formation GO-BP term across the different datasets. A negative and positive signed -log 10 P value were calculated through Gene Set Enrichment Analysis (GSEA) and indicates down- and upregulated expression, respectively. C log 2 odds ratio (OR) of differential expression in seizure- versus non-seizure-associated neurodevelopmental disorders for all genes associated with cerebellar Purkinje cell layer formation. LHX1 has the highest OR. The lines indicate different types of protein-protein and gene-gene relationships from GeneMANIA (version 3.5.3). D log 2 FC profile and their 95% confidence interval of the LHX1 gene in seizure- and non-seizure-associated neurodevelopmental disorders. E LHX1 expression levels across different <t>brain</t> regions in six different datasets available from the Human Protein <t>Atlas:</t> HPA (Human), FANTOM, GTEx, HPA (Pig), HPA <t>(Mouse),</t> and <t>Allen</t> Mouse Brain Atlas. The Z-score was calculated for each dataset separately. F UMAP plot of the cerebellar vermis scRNA-seq data from the Human Brain Atlas v1.0. The LHX1 expression in the different superclusters is shown. Specifically, 51 and 28% of the cerebellar inhibitory and upper rhombic lip cells, respectively, express LHX1 .
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    A Circular heatmap of the distribution of the eight neurological phenotypes across the 151 NDD datasets. B The signed -log 10 P value of the Cerebellar Purkinje cell layer formation GO-BP term across the different datasets. A negative and positive signed -log 10 P value were calculated through Gene Set Enrichment Analysis (GSEA) and indicates down- and upregulated expression, respectively. C log 2 odds ratio (OR) of differential expression in seizure- versus non-seizure-associated neurodevelopmental disorders for all genes associated with cerebellar Purkinje cell layer formation. LHX1 has the highest OR. The lines indicate different types of protein-protein and gene-gene relationships from GeneMANIA (version 3.5.3). D log 2 FC profile and their 95% confidence interval of the LHX1 gene in seizure- and non-seizure-associated neurodevelopmental disorders. E LHX1 expression levels across different <t>brain</t> regions in six different datasets available from the Human Protein <t>Atlas:</t> HPA (Human), FANTOM, GTEx, HPA (Pig), HPA <t>(Mouse),</t> and <t>Allen</t> Mouse Brain Atlas. The Z-score was calculated for each dataset separately. F UMAP plot of the cerebellar vermis scRNA-seq data from the Human Brain Atlas v1.0. The LHX1 expression in the different superclusters is shown. Specifically, 51 and 28% of the cerebellar inhibitory and upper rhombic lip cells, respectively, express LHX1 .
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    A Circular heatmap of the distribution of the eight neurological phenotypes across the 151 NDD datasets. B The signed -log 10 P value of the Cerebellar Purkinje cell layer formation GO-BP term across the different datasets. A negative and positive signed -log 10 P value were calculated through Gene Set Enrichment Analysis (GSEA) and indicates down- and upregulated expression, respectively. C log 2 odds ratio (OR) of differential expression in seizure- versus non-seizure-associated neurodevelopmental disorders for all genes associated with cerebellar Purkinje cell layer formation. LHX1 has the highest OR. The lines indicate different types of protein-protein and gene-gene relationships from GeneMANIA (version 3.5.3). D log 2 FC profile and their 95% confidence interval of the LHX1 gene in seizure- and non-seizure-associated neurodevelopmental disorders. E LHX1 expression levels across different <t>brain</t> regions in six different datasets available from the Human Protein <t>Atlas:</t> HPA (Human), FANTOM, GTEx, HPA (Pig), HPA <t>(Mouse),</t> and <t>Allen</t> Mouse Brain Atlas. The Z-score was calculated for each dataset separately. F UMAP plot of the cerebellar vermis scRNA-seq data from the Human Brain Atlas v1.0. The LHX1 expression in the different superclusters is shown. Specifically, 51 and 28% of the cerebellar inhibitory and upper rhombic lip cells, respectively, express LHX1 .
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    A Circular heatmap of the distribution of the eight neurological phenotypes across the 151 NDD datasets. B The signed -log 10 P value of the Cerebellar Purkinje cell layer formation GO-BP term across the different datasets. A negative and positive signed -log 10 P value were calculated through Gene Set Enrichment Analysis (GSEA) and indicates down- and upregulated expression, respectively. C log 2 odds ratio (OR) of differential expression in seizure- versus non-seizure-associated neurodevelopmental disorders for all genes associated with cerebellar Purkinje cell layer formation. LHX1 has the highest OR. The lines indicate different types of protein-protein and gene-gene relationships from GeneMANIA (version 3.5.3). D log 2 FC profile and their 95% confidence interval of the LHX1 gene in seizure- and non-seizure-associated neurodevelopmental disorders. E LHX1 expression levels across different brain regions in six different datasets available from the Human Protein Atlas: HPA (Human), FANTOM, GTEx, HPA (Pig), HPA (Mouse), and Allen Mouse Brain Atlas. The Z-score was calculated for each dataset separately. F UMAP plot of the cerebellar vermis scRNA-seq data from the Human Brain Atlas v1.0. The LHX1 expression in the different superclusters is shown. Specifically, 51 and 28% of the cerebellar inhibitory and upper rhombic lip cells, respectively, express LHX1 .

    Journal: Communications Biology

    Article Title: Integrative analysis of 115 transcriptomic studies decodes the molecular landscape of neurodevelopmental disorders

    doi: 10.1038/s42003-025-08330-2

    Figure Lengend Snippet: A Circular heatmap of the distribution of the eight neurological phenotypes across the 151 NDD datasets. B The signed -log 10 P value of the Cerebellar Purkinje cell layer formation GO-BP term across the different datasets. A negative and positive signed -log 10 P value were calculated through Gene Set Enrichment Analysis (GSEA) and indicates down- and upregulated expression, respectively. C log 2 odds ratio (OR) of differential expression in seizure- versus non-seizure-associated neurodevelopmental disorders for all genes associated with cerebellar Purkinje cell layer formation. LHX1 has the highest OR. The lines indicate different types of protein-protein and gene-gene relationships from GeneMANIA (version 3.5.3). D log 2 FC profile and their 95% confidence interval of the LHX1 gene in seizure- and non-seizure-associated neurodevelopmental disorders. E LHX1 expression levels across different brain regions in six different datasets available from the Human Protein Atlas: HPA (Human), FANTOM, GTEx, HPA (Pig), HPA (Mouse), and Allen Mouse Brain Atlas. The Z-score was calculated for each dataset separately. F UMAP plot of the cerebellar vermis scRNA-seq data from the Human Brain Atlas v1.0. The LHX1 expression in the different superclusters is shown. Specifically, 51 and 28% of the cerebellar inhibitory and upper rhombic lip cells, respectively, express LHX1 .

    Article Snippet: The brain region-specificity of genes of interest was assessed using the six available brain RNA expression datasets from the Human Protein Atlas (version 24.0): HPA (Human), FANTOM, GTEx, HPA (Pig), HPA (Mouse), and Allen Mouse Brain Atlas.

    Techniques: Expressing, Quantitative Proteomics